For the Doctors

 Do you have patients that seem to be on a chronic course?  Who are considered at MMI but are still in pain? Do they have a non fragmented disc herniation or advanced DJD? Are you puzzled why there not improving?  Not a good surgical candidate? 

Please read on...

Chronic neck and back pain that  improves after your care only to have them slide back if they miss a few appointments? I know your frustration... 

They may have one or more of these conditions:

  • Fibrosis adhesions, the stubborn buildups of scar tissue in and around the spinal joints (kinisiopathology).  
  • Have an unfragmented herniated disc and chronic disc problems and are unable to tolerate the moderate discomforts of traditional physical therapy chiropractic adjustments and are not responding to pain meds? 
  • Do their bodies involuntarily resist standard care or manipulation, does acute myofascial pain syndrome keep coming back?
  • Haven't responded satisfactorily to several months of chiropractic spinal adjustments, pain management therapy for neck pain or low-back pain.
  • Did they have back surgery that failed to relive their pain, or they're recovering from another type of surgery and are experiencing spinal pain?


Please  see the lists of references to this possible approach, that is curative...


Have you or someone you know been advised to undergo spinal surgery to relieve low-back pain? Research reveals that many spinal surgeries are not medically necessary and that conservative alternatives  can provide lasting results without the dangers of surgery.

No Rush, No Regrets

Rare cases of back pain associated with severe nerve degeneration (for example, cases involving bowel or bladder dysfunction) may require immediate surgery. Cases involving fracture or major trauma may also justify immediate medical surgical intervention. 

However, in most cases, there is no need to rush spinal surgery

"Only 0.25 percent of individuals with back problems require surgery," said spinal expert Dr. J. Kraemer at the annual meeting of International Society for the Study of the Lumbar Spine in Seattle, WA. (0.25 percent is only 1 in 400)

Despite Popular Opinion ...

In some cases, surgery is recommended to correct spinal degeneration, such as osteoarthritis. However, the link between back pain and the occurrence of these abnormalities is weak (N Eng J Med 1994;331:6073). Signs of degeneration can be found, via x-ray, in virtually anyone over the age of 40. And, according to medical experts, intervertebral disc herniation or lesions are not necessarily a reason for surgery (Spine 1998;21:245). Specifically:

More than 90 percent of patients with disc herniation improve with conservative non-surgical care.

Only 2 to 4 percent of patients with disc herniations meet medical criteria for surgical intervention.

Magnetic Resonance Imaging (MRI) will reveal a disc herniation in approximately 20 percent of pain-free people under the age of 60, indicating that a person with back pain may have an unrelated, asymptomatic disc lesion.

Over time, most patients with disc herniations recover with or without surgery. Five-year outcomes are similar when surgical and non-surgical approaches are compared.

Failed Back-Surgery Syndrome

 For those who choose surgery, it's often not the solution they've been searching for. Up to 40 percent of patients experience a condition termed failed back-surgery syndrome (FBSS), which is characterized by unremitting pain and functional impairment. In rare cases, patients' symptoms actually increase following surgery. According to one report, 17 percent (Spine 1988;13:1418-22) of individuals who undergo back surgery require a second operation.

Why you should consider MUA/FRP for your chronic spinal cases?

Research Articles: 

 

1.       Low Back Pain Of Mechanical Origin: Randomized Comparison Of Chiropractic And Hospital Outpatient Treatment, 1990, BMJ. Conclusions: "For patients with low back pain in whom manipulation is not contraindicated chiropractic almost certainly confers worthwhile, long term benefit in comparison with hospital outpatient management. The benefit is seen mainly in those with chronic or severe pain. Introducing chiropractic into NHS practice should be considered."

2.       Randomized Comparison Of Chiropractic And Hospital Outpatient Management For Low Back Pain: Results From An Extended Follow-up, 1995, BMJ. Conclusions: "At three years the results confirm the findings of an earlier report that when chiropractic or hospital therapists treat patients with low back pain as they would in day to day practice those treated by chiropractic derive more benefit and long term satisfaction than those treated by hospitals."

3.       Outcome Of Low Back Pain In General Practice: A Prospective Study, 1998, BMJ. Conclusions: "The results are consistent with the interpretation that 90% of patients with low back pain in primary care will have stopped consulting with symptoms within three months. However, most will still be experiencing low back pain and related disabilty one year after consultation."

4.       Effects Of Unilateral Spinal Adjustments On Goinometrically-Assessed Cervical Lateral-Bending End-Range Asymmetry In Otherwise Asymptomatic Subjects, 1989, JMPT. This study confirms that an appropriate spinal adjustment can predictably normalize abnormal cervical spine motions.

5.       An Evaluation Of Medical And Chiropractic Provider Utilization And Costs: Treating Injured Workers In North Carolina, 2004, JMPT. Conclusions: "These data, with the acknowledged limitations of an insurance database, indicated lower treatment costs, less workdays lost, lower compensation payments, and lower utilization of management, the use of chiropractic services in North Carolina appear very low."

6.       Efficacy Of Spinal Manipulation And Mobilization For Low Back Pain And Neck Pain: A Systematic Review And Best Evidence Synthesis, 2003, The Spine Journal. Results: "There is limited to moderate evidence that SMT is better than physical therapy and home back exercise in both the long and short term….."

7.       Long-Term Follow-up Of A Randomized Clinical Trial Assessing The Efficacy Of Medication, Acupuncture, And Spinal Manipulation For Chronic Mechanical Spinal Pain Syndromes, 2005, JMPT. Conclusions: "In patients with chronic spinal pain syndromes, spinal manipulation, if not contraindicated, may be the only treatment modality of the assessed regimens that provides broad and significant long-term benefit."

8.       Efficacy Of Preventive Spinal Manipulation For Chronic Low-Back Pain And Related Disabilities: A Preliminary Study, 2004 JMPT. Conclusions: "Intensive spinal manipulation is effective for the treatment of chronic low back pain. This experiment suggests that maintenance spinal manipulations after intensive manipulative care may be beneficial to patients to maintain subjective postintensive treatment disability levels. Further studies, however, are needed to confirm the finding in a larger group of patients with chronic low-back pain."

9.       Chiropractic Effects On Athletic Ability, 1991, JCR. Athletic ability was increased with chiropractic care as compared to a control group.

10.     Objective Physiologic Changes And Associated Health Benefits Of Chiropractic Adjustments In Asymptomatic Subjects: A Review Of The Literature, 2004 JVSR. Conclusions: "The data reviewed lend support to the contention that chiropractic adjustments, often for the purpose of correcting vertebral subluxation, confer measurable health benefits to people regardless of the presence of absence of symptoms...   

 

Additional References 

 1) Manipulation Under Anesthesia: A Report Of Four Cases, JMPT, 9.2005 Four patients that had not improved adequately to numerous months of in-office chiropractic management improved substantially after MUA/FRP procedures. This study also reports a 70% success rate found during a Quality Assurance review of the surgery center where MUA cases are performed. 70% of patients interviewed after MUA procedures reported that they were very satisfied with the improvement that they obtained from the procedure. This recent MUA study confirms the findings of other researchers that reported similar results.

2) Frank Kohlbeck , DC and Scott Haldeman, DC, MD, PhD, published a literature review of MUA ( 49 published articles) in THE SPINE JOURNAL in (2002) Medication Assisted Spinal Manipulation and concluded the following:

Medicine-assisted spinal manipulation therapies have a relatively long history of clinical use and have been reported in the literature for over 70 years. Page 288

Recent advances in highly titratable and reversible intravenous anesthesia have significantly reduced risks associated with manipulation under anesthesia (MUA), analgesia and sedation, which can now be performed in outpatient surgical centers. Page 289

There are case reports and case series describing the successful use of MUA and other medically assisted manual therapies in patients …” Page 289

The rationale for the use of MUA is that anesthesia and analgesia help to eliminate or reduce pain and muscle spasm that hinder the effective use of traditional manipulation to break up joint adhesions and reduce segmental dysfunction to a greater extent than if anesthesia had not been employed. Page 289

The earliest MUA study was published in 1930 by The Lancet overall 75 percent of patients improved. Page 290

In a first study by Siehl ad Bradford published in 1952, 33 percent of the patients demonstrated good (symptom-free) results. Page 294

Siehls followup study 96 percent reported successful (good or fair) outcomes.

Mesners study included 205 patients 51 percent of the patients reported satisfactory results. Page 294

In Chrismans study 83 percent of the subjects reported good or excellent result after a 3-year follow-up. Page 294

In Moreys 1973 review treating physician reported excellent or good results in 85 percent of the cases. Page 294

In a study published in 1986 by Krumhansel and Nowacek outcomes were reported as 25 percent cured, 50 percent much improved, and 20 percent better, but. Page 294

In a 1990 article by Mennell 30 percent with symptoms cured, 35 percent with marked improvement, 29 percent with moderate improvement…” Page 294

In a recent case series by West et al VAS scores improved 4.6 points for cervical pain and 4.31 points for lumbar pain. Decrease in time off work and less use of prescription pain medication were also reported. Page 294 (This is the ONLY article reviewed by ACOEM and somehow led to their conclusion of not recommended)

Current procedures more commonly use specific, short-lever, high velocity low amplitude thrusts characteristic of chiropractic and modern osteopathic adjustive techniques in addition to mobilization. Page 294

A typical MUA procedure involves placing the patient in a twilight anesthesia by a board-certified anesthesiologist while the clinician with the aid of a skilled assistant provides specific mobilization and manipulation techniques to the affected joints and spinal regions. Page 294

Current guidelines recommend the presence of a primary physician and assisting physician who have both undergone adequate training in MUA procedures. An assistant is necessary to position the patient and stabilize the sedated patient. Page 295

We have been unable to find any report of complications using more modern osteopathic and chiropractic techniques or as a result of the use of anesthesia. Page 297

If a clinician recommends MUA it would be difficult to deny the use of medication-assisted manipulation or fail to reimburse for it.

The literature (a PubMed search from 1966) consists primarily of case reports and case series with two randomized controlled trials and one cohort study.

3) Supplemental Care With Medication-Assisted Manipulation Versus Spinal Manipulation Therapy Alone For Patients With Chronic Low Back Pain, 2005 JMPT 

Medication-assisted manipulation appears to offer patients increased improvement in low back pain and disability when compared to usual chiropractic care. Page 258

The relative odds of experiencing a 10-point improvement in pain and disability favored the medication-assisted manipulation group at 3 months and one year. Page 258

4) Daniel West et al reported in a JMPT 1999;22(5) study titled Effective Management of Spinal Pain in 177 Patients Evaluated for MUA 

VAS ratings improved by 62.2 percent in those patients with cervical pain problems and 60.1 percent in those patients with lumbar pain problems. There was a near-complete reversal (68 percent) in patients out of work before MUA, and those returning to unrestricted activities at 6 months after MUA totaled 64.1 percent. There was a 58.4 percent reduction in the percentage of patients requiring prescription pain medication from the pre-MUA period to 6 months after MUA. Additionally, 24 percent of the treatment group required no medication at 6 months after MUA. Page 299

The addition of anesthetic allows for the benefits of manipulation to be shared with those patients who cannot tolerate manual techniques because of pain response, spasm, muscle contractures, and guarding. Page 300

MUA has been used successfully in treating those patients unresponsive to acute and chronic musculoskeletal conditions for years. Page 300

Only highly skilled, graduate practitioners who have been trained in structural diagnosis and manipulative treatments should be performing these procedures. Page 300

All patients with diagnosed spinal conditions received treatment in the area of primary diagnosis, as well as the areas superior and inferior. This is due to the anatomy of the ligamentous, tendinous, and muscular origins and insertions (i.e. if the lumbar spine is the primary site of injury, the treatment areas were thoracic, lumbar, and pelvic). Page 303

Performance of the MUA procedure requires a certified MUA first assistant for stabilization and patient positioning, as well as direct ancillary treatment. Page 304

We believe we have shown that this treatment program is safe and efficacious in comparison with other treatment options. Page 307

5) Palmieri et al , October 2002. Chronic LBP: A study of the effects of MUA. JMPT Oct 2002;25(8):E8] Demonstrated clinical efficacy of MUA performed in a series of three consecutive procedures. The average Numeric Pain Scale scores in the MUA group decreased by 50 percent, and the Roland-Morris Questionnaire scores decreased by 51 percent compared to a controlled group.

Existing methods for managing nonpathologic chronic back pain include patient education, back schools, spinal injections, medications, physical therapy, exercise and rehabilitation, acupuncture, spinal mobilization and manipulation, behavioral modification, and work and lifestyle activity modification. The MUA procedure is typically performed on patients who have received some or all of these treatments without favorable results. Page 2

6) Siehl D. Manipulation of the Spine under General Anesthesia. J Am Osteopath Assoc. June 1963;62:35-41. 

“… the reposition under anesthesia is harmless and presents absolutely an acknowledged and trustworthy procedure in treatment. Page 36

However, I believe that manipulation under anesthesia might well be the ideal treatment in many cases of acute low back and neck problems. Page 37

Of the patients having merely myofibrositis or a similar pathologic state, 96.3 percent were improved (good to fair results), making manipulation (under anesthesia) worth while. Page 38

It becomes evident from the review of these cases that manipulation of the spine under general anesthesia is a valuable procedure, but the cases must be specifically selected. Page 39

The steady spasm and the consequent postural defects combine with local pain, tetalgia, disturbances of the sympathetic nervous system, insomnia, and fatigue to form a vicious circle which magnifies the disability. Therefore, in an attempt to break up this vicious circle, manipulation of various types is carried out through the spinal areas. This can be applied more effectively in many cases with the patient under general anesthesia. Page 39

A high percentage of good results can be obtained with careful evaluation and selection of cases. Page 39

7) Davis CG, DC. Fernando CA, MD. Do Motta MA, DC. Manipulation of the Low Back Under General Anesthesia: Case Studies and Discussion. J of Neuromusculoskeletal System. Fall 1993;1(3):126-134. 

Following this course of treatments, there was marked improvement in pain, with improvement in the orthopedic and neurologic exam. Medication use was decreased and functional capacity increased. Page 126

Failed back surgery syndrome is a common indication for MUA. Page 126

MUA was presented to the patient as an option for attempting to improve pain control and functioning. The procedure resulted in marked symptomatic improvement immediately after the MUA. Additionally, functional ability improved in these patients for whom physicians had expressed little hope of recovery of normal function. Page 129

The cross-links bind collagen fibers so that movement is restricted. When subjected to a high-velocity thrust, these cross-links may be disrupted without a resultant inflammatory reaction that would occur if the collagen fibers were torn. Page 132

The two patients in this case report had prolonged symptoms, and each had a number of back surgeries with radiographically identified postoperative scarring. Page 132

The MUA procedure in these cases have had longer lasting results than previous surgeries, nerve blocks, or medications. Page 132

Reports of manipulation under anesthesia have gone back as far as 1930 when 

Riches reported successful treatment of 87 percent of his patients with chronic sciatica, and 92 percent with chronic sacroiliac strain with manipulation under anesthesia. Page 132.

Many of the techniques require at least two operators, since control of the weight of the patients body and of the extremities rest entirely with the operators when the patient is under general anesthesia. This is particularly important with treatment directed at the lumbar spine and pelvis. Page 133

The assistant operator is needed for the positioning and stabilization of the patient and to assist in manipulations. Page 133

Care must be taken not to manipulate too vigorously under anesthesia. Instead of trying to achieve full range of motion in one manipulation, it is often better to manipulate more gently on two or more occasions. Page 133

Mennell has stated than it is no more irrational to use anesthesia to provide relaxation and to avoid pain in joint manipulation than it is to use anesthesia for the reduction of fractures and dislocation or extracting a tooth. Page 133

Both patients also regarded their functional capacity as being much improved. Page 133

With patients who have undergone surgery only to have the pain return due to scar tissue and fibrosis, MUA may be beneficial. Page 134

8) Mennell J MCM , MD. The Validation of the Diagnosis Joint Dysfunction in the Synovial Joints of the Cervical Spine. JMPT Jan 1990;13(1):7-12. 

I use it (MUA) to obtain pure relaxation, for pain relief and sometimes for expedience never so that I may use more force or any different technique. Page 11

My manipulative techniques are exactly the same with the patient awake or asleep. It is interesting that when asleep the patients restricted joint movement (amount of loss of function) is exactly the same as when they are awake. Page 11

When a patient is anesthetized, the therapeutic techniques used are exactly the same, though they are performed even more gently. Page 11

9) Greenman PE, DO. Manipulation with the patient under anesthesia. JAOA Sept 1992;92(9):1159-1170.

Safety and effectiveness are favored by appropriate selection of patients, knowledge of indications and contraindications, suitable anesthetic, and services of a qualified physician trained in structural diagnosis and manipulative technique. Page 1159

The patient was symptom-free for the succeeding 18 months, …” Page 1160

The patients condition was greatly improved 24 hours after undergoing manipulation under anesthesia, and she was symptom-free within 10 days. No subsequent sequelae occurred for 18 months. Minor recurrence then responded quickly to more usual forms of manual medicine. Page 1160

The purpose of the anesthesia is to obliterate the pain and muscle spasm that has prevented other forms of conservative manual medicine care from being effective. Page 1167

Additionally, an experienced team can accomplish the procedure more quickly and save anesthesia time. Many of the techniques recommended require a minimum of two operators. Page 1167

10) Herzog J, DC. Use of Cervical Spine Manipulation Under Anesthesia for Management of Cervical Disk Herniation, Cervical Radiculopathy, and Associated Cervicogenic Headache Syndrome. JMPT Mar/Apr 1999;22(3):166-70. 

The patient had immediate relief after the first procedure. Her neck and arm pain were reported to be 50 percent better after the first trial, and her headaches were better by 80 percent after the third trial. Four months after the last procedure the patient reported a 95 percent improvement in her overall condition. Page 166

The generally accepted rationale for how MUA works is based on solid scientific data relating to muscle and joint physiology. Page 166

Siehl and Claybourne have documented the validity of MUA as a procedure useful in treating musculoskeletal disorders when restriction of the joint, joint capsule, and surrounding musculature has taken place as a result of the formation of fibrous adhesions. Page 166

She returned to work and maintained the improvement three months later. Page 168

The post-MUA therapy continues for a total of 6 to 8 weeks. At that time the patient will have achieved a maximum therapeutic benefit and be discharged. Rehabilitation and strengthening of the supporting tissues will help maintain the effects of the alteration of the fibrous adhesions that have occurred with the MUA. Page 169

Regardless, it seems to appear that MUA has a positive effect on certain types of conditions that have been unresponsive to traditional therapeutic approaches. Page 169

Significant increase in overall muscle flexibility and spinal range of motion was realized after each treatment. The rationale for MUA use is to control and alter the fibrous adhesions that are a result of the inflammatory cycle. Page 170

MUA has been shown to be of benefit in a case of cervical disk herniation with cervical radiculopathy and cervicogenic headache syndrome. Page 170

11) Rumney IC, DO. Manipulation of the Spine and Appendages under Anesthesia: An evaluation. JOAO. Nov. 1968;68:75-85. 

Tospon reports that, in treating over 200 cases of ligamentous strain of the neck due to auto accident, early manipulation under anesthesia (second or third week after the accident) lessened the morbidity and hastened the recovery. Page 76

In 1955 Mensor reported good results in 64 percent of private practice patients and 45 percent of patients whose disability was caused by industrial accidents. After 20 years experience and treatment of more than 600 patients with manipulation of the back under anesthesia he has had sufficiently satisfactory results to continue with this procedure. Page 76

When the condition advances to fibrosis one is faced with a prolonged program, and it is at this point that manipulative therapy under anesthesia is most frequently indicated. Page 77

Even after the manipulative procedures break up the fibrosis, one must institute an adequate program of physical therapy and exercise. If one does not prevent, or lessen, the formation of fibrous tissue, the patients original problem will recur. Page 77

I believe there is a definite place for MUA. The procedure would definitely obviate the need for back surgery in many cases. Page 85

Only physicians who are well trained in the art of manipulative therapy should employ anesthesia for such procedures. Page 85.

12) Samuel Turek , MD , orthopedic surgeon, reports in his textbook, Principles and Applications of Orthopedics.

good to excellent results can be expected in 50 percent of patients with acute herniated nucleus pulposis with MUA.

13) Thomas Dorman , MD , Orthopedist, Diagnosis Techniques in Orthopedic Medicine. MUA is recommended when the patient has failed at conservative in-office care.

14) Robert Mensor , MD , orthopedic surgeon. Lumbar Vertebral Disc Syndrome. Conducted a large clinical trial of over 600 patients with EMG verified radiculopathy and found that 83 percent responded well to MUA.

15) Christman OD , MD. et al. A Study of the Results Following Rotatory Manipulation in the Lumbar IVD Syndrome. J Bone and Joint Surgery. 1964 Apr;46-A(3) reported that 51 percent of patients with unrelieved symptoms after conservative care had good to excellent results even three years after MUA.   

Read Dr. Gerge Kosmides' original article on Manipulation Under Anesthesia

 

George Kosmides DC, CMUA

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